-
Product Name
TGM1 antibody
- Documents
-
Description
TGM1 Rabbit Polyclonal antibody. Positive IHC detected in human cervix tissue, human cervical cancer tissue, human skin tissue. Positive IP detected in mouse kidney tissue. Positive WB detected in mouse kidney tissue, mouse thymus tissue. Observed molecular weight by Western-blot: 90kd
-
Tested applications
ELISA, IP, WB, IHC
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
Epidermal TGase antibody; ICR2 antibody; KTG antibody; LI1 antibody; TG(K) antibody; TGASE antibody; TGase 1 antibody; TGase K antibody; TGK antibody; TGM1 antibody; Transglutaminase 1 antibody; Transglutaminase K antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of TGM1 recombinant protein (Accession Number: NM_000359). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:500-1:5000
IHC: 1:50-1:600
-
Validations
mouse kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:116028(TGM1 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human cervix using Catalog No:116028(TGM1 antibody) at dilution of 1:200 (under 10x lens)
Immunohistochemical of paraffin-embedded human cervix using Catalog No:116028(TGM1 antibody) at dilution of 1:200 (under 40x lens)
IP Result of anti-TGM1 (IP:Catalog No:116028, 4ug; Detection:Catalog No:116028 1:1000) with mouse kidney tissue lysate 4000ug.
-
Background
Transglutaminase 1 is a epidermal enzyme that is expressed during the terminal differentiation of keratinized squamous epithelium to form cornified cell envelope in differentiated keratinocytes. Mutation of TGM1 has been linked to various epidermal diseases. This antibody recognizes the endogenous 90 kDa TGM1 proteins.
-
References
- Dang NN, Pang SG, Song HY, An LG, Ma XL. Filaggrin silencing by shRNA directly impairs the skin barrier function of normal human epidermal keratinocytes and then induces an immune response. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ...
- Dang NN, Pang SG, Song HY, An LG, Ma XL. Filaggrin silencing by shRNA directly impairs the skin barrier function of normal human epidermal keratinocytes and then induces an immune response. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ...
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"