TAX1BP3 antibody

TAX1BP3 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

TAX1BP3 Rabbit Polyclonal antibody. Positive WB detected in mouse ovary tissue, A2780 cells. Positive IHC detected in human small intestine tissue, human kidney tissue, human lung cancer tissue. Observed molecular weight by Western-blot: 15-17kd

ELISA, WB, IHC

Human,Mouse,Rat; other species not tested.

Tax interaction protein 1 antibody; Tax1 binding protein 3 antibody; TAX1BP3 antibody; TIP 1 antibody; TIP1 antibody

Rabbit IgG

This antibody was obtained by immunization of TAX1BP3 recombinant protein (Accession Number: NM_014604). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Tax-interacting protein 1 (TIP-1, also known as Tax1bp3 or glutaminase-interacting protein, GIP) is unique in its simple structure, a single PDZ domain is the only functional and structural unit identified so far in this small PDZ protein (124 amino acids in human and mouse). High level of TIP-1 expression was detected in human invasive breast cancer cells and that is important for tumor cell adhesion, migration and pulmonary metastasis. However, the precise biological effects of TIP-1 and its functional mechanisms have largely remained elusive. Mutation of TAX1BP3 can cause Dilated Cardiomyopathy with Septo-Optic Dysplasia (PMID: 25645515).