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Syntenin 2 antibody

Cat.#: 115802

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Product Information

  • Product Name
    Syntenin 2 antibody
  • Documents
  • Description
    Syntenin 2 Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer tissue, human gliomas tissue. Positive WB detected in mouse brain tissue, human liver tissue, mouse heart tissue. Observed molecular weight by Western-blot: 35-37kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    FLJ12256 antibody; SDCBP2 antibody; SITAC18 antibody; ST 2 antibody; Syndecan binding protein 2 antibody; Syntenin 2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Syntenin 2 recombinant protein (Accession Number: NM_015685). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115802(SDCBP2 antibody) at dilution of 1:1000

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115802(SDCBP2 antibody) at dilution of 1:1000

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:115802(SDCBP2 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:115802(SDCBP2 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:115802(SDCBP2 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:115802(SDCBP2 Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    Syndecan-binding protein 2 (SDCBP2, Syntenin 2) is a protein containing two PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins. SDCBP2 binds with high affinity to PIP2 and is targeted to the plasma membrane, nucleoli and nuclear speckles via its PDZ domains (PMID: 15961997). SDCBP2 exists in two alternatively spliced variants, 2α and 2β, which differ in the lengths of their N-terminal regions. (PMID: 15276154)
  • References
    • Lazić D, Hufbauer M, Zigrino P. Human papillomavirus type 8 E6 oncoprotein inhibits transcription of the PDZ protein syntenin-2. Journal of virology. 86(15):7943-52. 2012.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"