-
Product Name
STT3B antibody
- Documents
-
Description
STT3B Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, mouse liver tissue. Observed molecular weight by Western-blot: 94 kDa
-
Tested applications
ELISA, WB
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
FLJ90106 antibody; SIMP antibody; STT3 B antibody; STT3B antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of STT3B recombinant protein (Accession Number: BC015880). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:1000-1:10000
-
Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115740(STT3B antibody) at dilution of 1:2000
-
Background
STT3B is a component of the N-oligosaccharyl transferase (OST) enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3B seems to be involved in complex substrate specificity
-
References
- Horak P, Tomasich E, Vaňhara P. TUSC3 loss alters the ER stress response and accelerates prostate cancer growth in vivo. Scientific reports. 4:3739. 2014.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"