SRP19 antibody

SRP19 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

SRP19 Rabbit Polyclonal antibody. Positive WB detected in human liver tissue, A549 cells, HeLa cells, K-562 cells, mouse kidney tissue, mouse liver tissue, mouse ovary tissue, Raji cells. Positive IP detected in mouse kidney tissue. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 18-25 kDa

ELISA, WB, IP, IF

Human,Mouse,Rat; other species not tested.

SRP19 antibody

Rabbit IgG

This antibody was obtained by immunization of SRP19 recombinant protein (Accession Number: NM_003135). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

The signal recognition particle (SRP) is one of the few functional small RNP particles. The SRP couples the synthesis of membrane and secretory proteins across or into the endoplasmic reticulum (ER) membrane in eukaryotes, as well as across the bacterial plasma membrane, and chloroplast thylakoid membranes. The mammalian SRP is composed of a 7S (or 7SL) RNA and six different proteins, SRP9, SRP14, SRP19, SRP54, SRP68 and SRP72. All of the components of SRP, including SRP RNA, participate directly in the overall protein targeting process. SRP19 binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. SRP19 was shown to significantly enhance SRP54 attachment to helix 8 of 7SL RNA. Binding of SRP19 leads to restructuring of both helix 6 and 8, causing local changes at the SRP54-binding site. This antibody is a rabbit polyclonal antibody raised against full length SRP19 of human origin.