-
Product Name
SPTLC2 antibody
- Documents
-
Description
SPTLC2 Rabbit Polyclonal antibody. Positive WB detected in human stomach tissue. Observed molecular weight by Western-blot: 55-65 kDa
-
Tested applications
ELISA, WB
-
Species reactivity
Human, Mouse; other species not tested.
-
Alternative names
KIAA0526 antibody; LCB 2 antibody; LCB2 antibody; LCB2a antibody; Serine palmitoyltransferase 2 antibody; SPT 2 antibody; SPT2 antibody; SPTLC2 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_004863). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
-
Validations
human stomach tissue were subjected to SDS PAGE followed by western blot with Catalog No:115656(SPTLC2 antibody) at dilution of 1:300
-
Background
SPTLC2 represents serine palmitoyltransferase, long chain base subunit 2
-
References
- Hojjati MR, Li Z, Jiang XC. Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice. Biochimica et biophysica acta. 1737(1):44-51. 2005.
- Li Z, Li Y, Chakraborty M. Liver-specific deficiency of serine palmitoyltransferase subunit 2 decreases plasma sphingomyelin and increases apolipoprotein E levels. The Journal of biological chemistry. 284(39):27010-9. 2009.
- Altura BM, Shah NC, Li Z, Jiang XC, Perez-Albela JL, Altura BT. Magnesium deficiency upregulates serine palmitoyl transferase (SPT 1 and SPT 2) in cardiovascular tissues: relationship to serum ionized Mg and cytochrome c. American journal of physiology. Heart and circulatory physiology. 299(3):H932-8. 2010.
- Campbell-Valois FX, Trost M, Chemali M. Quantitative proteomics reveals that only a subset of the endoplasmic reticulum contributes to the phagosome. Molecular & cellular proteomics : MCP. 11(7):M111.016378. 2012.
- Camell CD, Nguyen KY, Jurczak MJ. Macrophage-specific de Novo Synthesis of Ceramide Is Dispensable for Inflammasome-driven Inflammation and Insulin Resistance in Obesity. The Journal of biological chemistry. 290(49):29402-13. 2015.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"