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Product Name
SNRPN antibody
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Description
SNRPN Rabbit Polyclonal antibody. Positive IF detected in SH-SY5Y cells. Positive IHC detected in human gliomas tissue. Positive WB detected in mouse brain tissue, HEK-293 cells, HeLa cells. Observed molecular weight by Western-blot: 27-30 kDa
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Tested applications
ELISA, WB, IHC, IF
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
DKFZp686C0927 antibody; DKFZp686M12165 antibody; DKFZp761I1912 antibody; DKFZp762N022 antibody; FLJ33569 antibody; FLJ36996 antibody; FLJ39265 antibody; HCERN3 antibody; PWCR antibody; RT LI antibody; SM D antibody; Sm N antibody; Sm protein D antibody; Sm protein N antibody; SMN antibody; SNRNP N antibody; SNRPN antibody; SNURF SNRPN antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SNRPN recombinant protein (Accession Number: BC010057). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115466(SNRPN antibody) at dilution of 1:800
Immunohistochemical of paraffin-embedded human gliomas using Catalog No:115466(SNRPN antibody) at dilution of 1:100 (under 10x lens)
Immunofluorescent analysis of SH-SY5Y cells, using SNRPN antibody Catalog No:115466 at 1:50 dilution and FITC-labeled donkey anti-rabbit IgG(green). Blue pseudocolor = DAPI (fluorescent DNA dye).
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Background
SNRPN, or SNURF-SNRPN, is a bicistronic imprinted gene that encodes 2 polypeptides, the SmN splicing factor, which is involved in RNA processing, and the SNRPN upstream reading frame (SNURF) polypeptide.The SNRPN gene is transcribed exclusively from the paternally inherited chromosome and shows highest expression in brain and heart. SNRPN may play a role in etiology of Prader-Willi syndrome.
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References
- Ma X, Wu MX, Zhang YL, Cui DM, Li MT, Wu KL. Difference of gene expression between the central and the peripheral epithelia of the bovine lens. Chinese medical journal. 122(9):1072-80. 2009.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"