SMARCA4 antibody

SMARCA4 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

SMARCA4 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, K-562 cells. Observed molecular weight by Western-blot: 180kd

ELISA, WB

human, mouse, rat; other species not tested.

SMARCA4 antibody; Protein brahma homolog 1 antibody; FLJ39786 antibody; ATP dependent helicase SMARCA4 antibody; hSNF2b antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_001128844). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

SMARCA4, also named as BAF190A, BRG1, SNF2B and SNF2L4, belongs to the SNF2/RAD54 helicase family. SMARCA4 is a transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. It is a component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. It is also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. The antibody is specific to SMARCA4.