-
Product Name
SLC25A13 antibody
- Documents
-
Description
SLC25A13 Rabbit Polyclonal antibody. Positive IP detected in mouse kidney tissue. Positive WB detected in Raji cells, A431 cells, HEK-293 cells, mouse kidney tissue, mouse liver tissue. Positive IHC detected in human colon cancer tissue. Observed molecular weight by Western-blot: 60-63kd
-
Tested applications
ELISA, WB, IHC, IP
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
ARALAR2 antibody; CITRIN antibody; CTLN2 antibody; SLC25A13 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of SLC25A13 recombinant protein (Accession Number: NM_014251). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:500-1:5000
IHC: 1:20-1:200
-
Validations
Raji cells were subjected to SDS PAGE followed by western blot with Catalog No:115323(SLC25A13 antibody) at dilution of 1:800
Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:115323(SLC25A13 antibody) at dilution of 1:100 (under 10x lens)
IP Result of anti-SLC25A13 (IP:Catalog No:115323, 4ug; Detection:Catalog No:115323 1:1000) with mouse kidney tissue lysate 4000ug.
-
Background
SLC25A13, also known as citrin, has been identified as a mitochondrial aspartate-glutamate carrier protein and may be implicated in metabolic compartmentation. It consists of 675 amino acid residues and harbors four EF-hands and six mitochondrial transmembranous (TM) spanners. Mutations in SLC25A13 gene cause adult-onset type II citrullinemia (CTLN2) and neonatal intrahepatic cholestasis (NICCD). The complete deletion or cleaved SLA25A13 proteins have been reported in patients with SLC25A13 mutation.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"