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Product Name
SLC13A4 antibody
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Description
SLC13A4 Rabbit Polyclonal antibody. Positive IF detected in HEK-293 cells. Positive WB detected in HEK-293 cells. Observed molecular weight by Western-blot: 69 kDa
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Tested applications
ELISA, WB, IF
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
NaS2 antibody; SLC13A4 antibody; SUT 1 antibody; SUT1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SLC13A4 recombinant protein (Accession Number: NM_012450). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IF: 1:20-1:200
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:115303(SLC13A4 antibody) at dilution of 1:500
Immunofluorescent analysis of (10% Formaldehyde) fixed HEK-293 cells using Catalog No:115303(SLC13A4 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
SLC13A4 (also known as SUT-1 or NaS2) belongs to the family of Na+-coupled anion transporters and mediates sulfate reabsorption in the high endothelial venules (HEV). Sulfate is an obligate nutrient for fetal development. Highly expressed in placenta, SLC13A4 has been proposed to play important physiological roles in maintaining high maternal serum sulfate levels during pregnancy and mediating sulfate supply to the fetus.
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References
- Dawson PA, Rakoczy J, Simmons DG. Placental, renal, and ileal sulfate transporter gene expression in mouse gestation. Biology of reproduction. 87(2):43. 2012.
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