SLC12A5-Specific antibody

Cat.#: 115300

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Product Information

  • Product Name
    SLC12A5-Specific antibody
  • Documents
  • Description
    SLC12A5-Specific Rabbit Polyclonal antibody. Positive IHC detected in human brain. Positive WB detected in human brain tissue. Observed molecular weight by Western-blot: 126kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    human, mouse, rat; other species not tested.
  • Alternative names
    SLC12A5 antibody; K Cl cotransporter 2 antibody; KCC2 antibody; Neuronal K Cl cotransporter antibody; hKCC2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_020708). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115300(SLC12A5-Specific antibody) at dilution of 1:300

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115300(SLC12A5-Specific antibody) at dilution of 1:300

    Immunohistochemical of paraffin-embedded human brain using Catalog No:115300(SLC12A5-Specific antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human brain using Catalog No:115300(SLC12A5-Specific antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human brain using Catalog No:115300(SLC12A5-Specific antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human brain using Catalog No:115300(SLC12A5-Specific antibody) at dilution of 1:100 (under 40x lens)

  • Background
    SLC12A5, also named as KCC2 and KIAA1176, belongs to the SLC12A transporter family. SLC12A5 mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. SLC12A5 is important for Cl- homeostasis in neurons. The antibody is specific to SLC12A5.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"