SFRS2 antibody

SFRS2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

SFRS2 Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in mouse brain tissue, A549 cells, mouse testis tissue, rat brain tissue. Observed molecular weight by Western-blot: 25-35 kDa

ELISA, WB, IP

Human,Mouse,Rat; other species not tested.

PR264 antibody; Protein PR264 antibody; SC 35 antibody; SC35 antibody; SFRS2 antibody; SFRS2A antibody; Splicing component antibody; 35 kDa antibody; Splicing factor SC35 antibody; SRp30b antibody; SRSF2 antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_003016). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

SFRS2, also named as PR264 and Splicing component, 35 kDa, belongs to the splicing factor SR family. SFRS2 is necessary for the splicing of pre-mRNA. Some residue of SFRS2 is modified by phosphorylase and acetylase after translation. The molecular weight of modified SFRS2 is 35-40kDa. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. It binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. SFRS2 can bind to beta-globin mRNA and commit it to the splicing pathway. The antibody has no cross reaction to SFRS2B.