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Product Name
SENP3 antibody
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Description
SENP3 Rabbit Polyclonal antibody. Positive WB detected in Y79 cells, HeLa cells. Positive IP detected in Y79 cells. Observed molecular weight by Western-blot: 65-70 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
DKFZp586K0919 antibody; DKFZp762A152 antibody; SENP3 antibody; Sentrin specific protease 3 antibody; SMT3IP1 antibody; SSP3 antibody; SUMO 1 specific protease 3 antibody; SUSP3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SENP3 recombinant protein (Accession Number: NM_015670). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
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Validations
Y79 cells were subjected to SDS PAGE followed by western blot with Catalog No:115109(SENP3 antibody) at dilution of 1:500
IP Result of anti-SENP3 (IP:Catalog No:115109, 4ug; Detection:Catalog No:115109 1:500) with Y79 cells lysate 2000ug.
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Background
SENP3(Sentrin-specific protease 3) is also named as SSP3, SUSP3 and belongs to the peptidase C48 family. It acts as an essential factor for ribosome biogenesis. SENP3 might regulate the sumoylation of other substrates through directly binding or mediating association with NPM1 at the nucleolus and other subcellular compartments.
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References
- Fanis P, Gillemans N, Aghajanirefah A. Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation. Molecular & cellular proteomics : MCP. 11(11):1263-73. 2012.
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