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Product Name
SEC63 antibody
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Description
SEC63 Rabbit Polyclonal antibody. Positive WB detected in A431 cells, HEK-293 cells, PC-3 cells. Positive IP detected in A431 cells. Observed molecular weight by Western-blot: 83 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ERdj2 antibody; PRO2507 antibody; SEC63 antibody; SEC63 homolog (S. cerevisiae) antibody; SEC63L antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SEC63 recombinant protein (Accession Number: NM_007214). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IP: 1:200-1:1000
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Validations
A431 cells were subjected to SDS PAGE followed by western blot with Catalog No:115090(SEC63 antibody) at dilution of 1:1000
IP Result of anti-SEC63 (IP:Catalog No:115090, 4ug; Detection:Catalog No:115090 1:300) with A431 cells lysate 2400ug.
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Background
SEC63 represents SEC63 homolog (S. cerevisiae)
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References
- Hassan H, Tian X, Inoue K. Essential Role of X-Box Binding Protein-1 during Endoplasmic Reticulum Stress in Podocytes. Journal of the American Society of Nephrology : JASN. 2015.
- Fedeles SV, So JS, Shrikhande A. Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity. The Journal of clinical investigation. 125(5):1955-67. 2015.
- Conti BJ, Devaraneni PK, Yang Z, David LL, Skach WR. Cotranslational stabilization of Sec62/63 within the ER Sec61 translocon is controlled by distinct substrate-driven translocation events. Molecular cell. 58(2):269-83. 2015.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"