SCUBE3 antibody

Cat.#: 115022

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Product Information

  • Product Name
    SCUBE3 antibody
  • Documents
  • Description
    SCUBE3 Rabbit Polyclonal antibody. Positive WB detected in mouse kidney tissue, mouse lung tissue. Positive IHC detected in human kidney tissue. Observed molecular weight by Western-blot: 130kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    CEGF3 antibody; DKFZp686B09105 antibody; DKFZp686B1223 antibody; DKFZp686D20108 antibody; FLJ34743 antibody; SCUBE3 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of SCUBE3 recombinant protein (Accession Number: NM_001303136). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

    IHC: 1:20-1:200

  • Validations

    mouse kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:115022(SCUBE3 antibody) at dilution of 1:300

    mouse kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:115022(SCUBE3 antibody) at dilution of 1:300

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:115022(SCUBE3 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:115022(SCUBE3 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:115022(SCUBE3 antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:115022(SCUBE3 antibody) at dilution of 1:50 (under 40x lens)

  • Background
    SCUBE3 is a secreted glycoprotein that belongs to the SCUBE family. Members of the SCUBE family are secreted plasma membrane-associated proteins characterised by a N-terminal signal peptide sequence, multiple EGF domains, a N-linked glycosylated spacer region and a C-terminal CUB region. SCUBE3 may play a role in bone cell biology (PMID: 15234972). It may also has a role in the regulation of cardiac growth and remodeling responses (PMID: 17442284). Besides, SCUBE3 has been reported to be involved in lung cancer progression (PMID: 21441952; 23420440).

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