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Product Name
SCO1 antibody
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Description
SCO1 Rabbit Polyclonal antibody. Positive WB detected in human heart tissue. Observed molecular weight by Western-blot: 30kd
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
SCO1 antibody; SCOD1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SCO1 recombinant protein (Accession Number: NM_004589). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:115012(SCO1 antibody) at dilution of 1:400
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Background
Human SCO1 and SCO2 are metallochaperones that are essential for the assembly of the catalytic core of cytochrome c oxidase (COX). SCO1 appears to be involved in the folding and assembly of cytochrome oxidase subunit II, and possibly of other proteins of this subcompartment. It is a 33 kDa protein which displays limited homology to members of the DnaJ family(PMID:14731768). It is also named as SCOD1 and belongs to the SCO1/2 family. It can exsit as a homodimer(PMID:16735468). Defects in SCO1 are a cause of mitochondrial complex IV deficiency (MT-C4D).
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