Product Name

RTN2 antibody

Documents

Description

RTN2 Rabbit Polyclonal antibody. Positive IHC detected in human skeletal muscle tissue. Positive WB detected in mouse skeletal muscle tissue, human skeletal muscle tissue. Observed molecular weight by Western-blot: 20-23kd

Tested applications

ELISA, IHC, WB

Species reactivity

Human,Mouse,Rat; other species not tested.

Alternative names

NSP like protein 1 antibody; NSP like protein I antibody; NSP2 antibody; NSPL1 antibody; NSPLI antibody; reticulon 2 antibody; RTN2 antibody

Isotype

Rabbit IgG

Preparation

This antibody was obtained by immunization of RTN2 recombinant protein (Accession Number: BC014244). Purification method: Antigen affinity purified.

Clonality

Polyclonal

Formulation

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions

Store at -20℃. DO NOT ALIQUOT

Applications

Recommended Dilution:

WB: 1:500-1:5000

IHC: 1:20-1:200

Validations

mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:114862(RTN2 Antibody) at dilution of 1:1000

Immunohistochemistry of paraffin-embedded human skeletal muscle slide using Catalog No:114862(RTN2 Antibody) at dilution of 1:50

Background

Reticulon (RTN) proteins are a group of membrane-bound proteins that largely reside in endoplasmic reticulum (ER) (PMID: 18177508). Reticulon proteins share a common sequence feature, the reticulon homology domain (RHD). They are involved in shaping the tubular endoplasmic reticulum network, membrane trafficking, inhibition of axonal growth, and apoptosis (PMID: 24218324). Four mammalian reticulons (RTN1-4) exist. Human RTN2 gene produces three isoforms termed RTN2-A, RTN2-B, and RTN2-C. Isoform RTN2-C has a calculated molecular weight of 22 kDa and is highly expressed in skeletal muscle.

RTN2 antibody

Product Information

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