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Product Name
RNF34 antibody
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Description
RNF34 Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer tissue. Positive WB detected in Transfected HEK-293 cells.
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CARP 1 antibody; Caspase regulator CARP1 antibody; FLJ21786 antibody; FYVE RING finger protein Momo antibody; hRFI antibody; RFI antibody; RIF antibody; RIFF antibody; ring finger protein 34 antibody; RING finger protein RIFF antibody; RNF34 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of RNF34 recombinant protein (Accession Number: NM_025126). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:114757(RNF34 antibody) at dilution of 1:50 (under 10x lens)
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:114757(RNF34 Antibody) at dilution of 1:1000
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Background
RNF34(ring finger protein 34) has E3 ubiquitin-protein ligase activity and regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradationis.It is preferentially expressed in esophageal, gastric, and colorectal cancers, suggesting a possible association between RNF34 and the development of digestive tract cancers.Western blot results show the MW of 42-46kd,60kd,130kd.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"