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RHOC antibody

Cat.#: 114660

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Special Price 239.0 USD

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Product Information

  • Product Name
    RHOC antibody
  • Documents
  • Description
    RHOC Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, C6 cells, NIH/3T3 cells. Observed molecular weight by Western-blot: 22 kDa
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    ARH9 antibody; ARHC antibody; Rho cDNA clone 9 antibody; RHOC antibody; RHOH9 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of RH℃ recombinant protein (Accession Number: NM_001042679). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:114660(RHoc antibody) at dilution of 1:500

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:114660(RHoc antibody) at dilution of 1:500

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with Catalog No:114660(RHoc antibody) at dilution of 1:500

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with Catalog No:114660(RHoc antibody) at dilution of 1:500

  • Background
    Ras homolog family member C (RHoc) encodes a Rho-related GTP-binding protein, which belongs to small GTPase superfamily and also Rho family. RHoc. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Expression of RHoc contributes to metastatic phenotype of melanoma cells and is associated with multiple cancers including gastric carcinomas, ovarian carcinomas and breast cancer as well.
  • References
    • Gao Y, Song C, Hui L. Overexpression of RNF146 in non-small cell lung cancer enhances proliferation and invasion of tumors through the Wnt/β-catenin signaling pathway. PloS one. 9(1):e85377. 2014.
    • Zeng Z, Bo H, Gong Z. AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015.
    • Bo H, Gong Z, Zhang W. Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma. Oncotarget. 6(24):20404-18. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"