RGS9 antibody

Cat.#: 114650

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Product Information

  • Product Name
    RGS9 antibody
  • Documents
  • Description
    RGS9 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, SH-SY5Y cells. Observed molecular weight by Western-blot: 58kd,70-75kd
  • Tested applications
    ELISA, WB
  • Species reactivity
    human, mouse, rat; other species not tested.
  • Alternative names
    RGS9 antibody; PERRS antibody; RGS9L antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of RGS9 recombinant protein (Accession Number: BC022504). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114650(RGS9 antibody) at dilution of 1:500

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114650(RGS9 antibody) at dilution of 1:500

  • Background
    RGS9 is a member of the RGS family of signaling proteins that suppress the activity of G proteins by promoting their deactivation. There are two splice isoforms of RGS9 with quite different properties and patterns of expression. RGS9-1 is mainly found in the eye and is involved in regulation of phototransduction in rod and cone cells of the retina, while RGS9-2 is is expressed specifically in the striatum, a brain region involved in controlling movement, motivation, mood and addition. This antibody got about 58kD in the mouse eye and 70kD in the mouse brain in western blotting, both in line with their expected masses. Defects in RGS9 are a cause of prolonged electroretinal response suppression (PERRS).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"