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Product Name
RGS5 antibody
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Description
RGS5 Rabbit Polyclonal antibody. Positive WB detected in human heart tissue, human skeletal muscle tissue, MCF7 cells, mouse heart tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue. Positive IHC detected in human prostate cancer. Observed molecular weight by Western-blot: 42kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
RGS5 antibody; MST092 antibody; MSTP032 antibody; MSTP129 antibody; MST129 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of RGS5 recombinant protein (Accession Number: NM_003617). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:114648(RGS5 antibody) at dilution of 1:400
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:114648(RGS5 antibody) at dilution of 1:50 (under 10x lens)
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Background
RGS5 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. The 42kd band recognized by this antibody is a RGS5-RGS5 dimer. (Pubmed:17762159)
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"