RBM4 antibody

RBM4 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

RBM4 Mouse Monoclonal antibody. Positive WB detected in HeLa cells, fetal human brain tissue. Positive IHC detected in human cervical cancer tissue, human stomach tissue. Observed molecular weight by Western-blot: 40 kDa

ELISA, WB, IHC

Human; other species not tested.

DKFZp547K0918 antibody; hLark antibody; LARK antibody; Lark homolog antibody; RBM4 antibody; RBM4A antibody; RNA binding motif protein 4 antibody; RNA binding motif protein 4a antibody; RNA binding protein 4 antibody; ZCCHC21 antibody; ZCRB3A antibody

Mouse IgG2a

This antibody was obtained by immunization of RBM4 recombinant protein (Accession Number: BC021120). Purification method: Protein A purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

RBM4, RNA-binding motif protein4, contains 2 RRM-type RNA-binding motif and a retroviral-type(RT) zinc finger. RNA-binding factor participates in number of aspects of cellular processes such as alternative splicing of pre-mRNA and translation regulation. RBM4 recruits eIF4A1 to stimulate IRES-dependent translation in responds to cellular stress. Once assembled at the rHRE, the HIF2A-RBM4-eIF4E2 complex captures the 5-prime cap and targets mRNAs to polysomes for active translation, thereby evading hypoxia-induced repression of protein synthesis.