RAB3GAP2 antibody

Cat.#: 114446

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    RAB3GAP2 antibody
  • Documents
  • Description
    RAB3GAP2 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Positive IHC detected in human brain tissue, human cerebellum tissue. Observed molecular weight by Western-blot: 110 / 130 / 150 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human, Mouse, Rat; other species not tested.
  • Alternative names
    DKFZp434D245 antibody; FLJ14579 antibody; KIAA0839 antibody; p150 antibody; Rab3 GAP p150 antibody; Rab3 GAP regulatory subunit antibody; RAB3 GAP150 antibody; RAB3GAP150 antibody; RAB3GAP2 antibody; RGAP iso antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of RAB3GAP2 recombinant protein (Accession Number: NM_012414). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114446(RAB3GAP2 Antibody) at dilution of 1:600

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114446(RAB3GAP2 Antibody) at dilution of 1:600

    Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:114446(RAB3GAP2 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:114446(RAB3GAP2 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:114446(RAB3GAP2 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:114446(RAB3GAP2 Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    RAB3GAP2, also known as RAB3-GAP150, belongs to the Rab3-GAP regulatory subunit family. Rab3 GAP consists of two subunits: the catalytic subunit p130 and the noncatalytic subunit p150. Rab3 GAP is ubiquitously expressed and enriched in the synaptic soluble fraction of brain, consistent with it having a key role in neurodevelopment. RAB3-GAP150 forms the Rab3 GTPase-activating complex with RAB3-GAP130,where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. Defects in RAB3-GAP150 are the cause of Martsolf and Warburg Micro syndrome.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"