-
Product Name
RAB31-specific antibody
- Documents
-
Description
RAB31-specific Rabbit Polyclonal antibody. Positive WB detected in human brain tissue. Positive IHC detected in human heart tissue. Observed molecular weight by Western-blot: 22 kDa
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
Rab22B antibody; RAB31 antibody; Ras related protein Rab 22B antibody; Ras related protein Rab 31 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_006868). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
-
Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114430(RAB31-specific antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human heart tissue slide using Catalog No:114430(RAB31-specific Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human heart tissue slide using Catalog No:114430(RAB31-specific Antibody) at dilution of 1:50 (under 40x lens)
-
Background
RAB 31, also named as RAB22b, belongs to small GTP-binding proteins of the RAB family. Rab31 localizes in the trans-Golgi network (TGN) and endosomes. It is required for transport of mannose 6-phosphate receptors (MPRs) from the trans-Golgi network (TGN) to endosomes. This antibody can bind RAB31 specifically, and not react RAB22a.
-
References
- Yuan F, Snapp EL, Novikoff PM. Human liver cell trafficking mutants: characterization and whole exome sequencing. PloS one. 9(1):e87043. 2014.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"