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Product Name
Rab18 antibody
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Description
Rab18 Mouse Monoclonal antibody. Positive WB detected in Human adrenal gland, mouse testis tissue. Observed molecular weight by Western-blot: 23 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
RAB18 antibody; RAB18LI1 antibody; Ras related protein Rab 18 antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of Rab18 recombinant protein (Accession Number: NM_021252). Purification method: Caprylic acid/ammonium sulfate precipitation.
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Clonality
Monoclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
human adrenal gland tissue were subjected to SDS PAGE followed by western blot with Catalog No:107491(RAB18 antibody) at dilution of 1:1000
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Background
RAB18 is a member of a family of Ras-related small GTPases. RAB18 plays a role in apical endocytosis/recycling, and may be implicated in transport between the plasma membrane and early endosomes. It also plays a key role in eye and brain development and neurodegeneration. Defects in RAB18 are associated with Warburg micro syndrome type 3.
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References
- Gerondopoulos A, Bastos RN, Yoshimura S. Rab18 and a Rab18 GEF complex are required for normal ER structure. The Journal of cell biology. 205(5):707-20. 2014.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"