PTPRR antibody

PTPRR antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PTPRR Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, COLO 320 cells, HeLa cells. Observed molecular weight by Western-blot: 32kd,47kd,65kd

ELISA, WB

Human,Mouse,Rat; other species not tested.

Ch 1PTPase antibody; DKFZp781C1038 antibody; EC PTP antibody; ECPTP antibody; FLJ34328 antibody; NC PTPCOM1 antibody; PCPTP1 antibody; PTP SL antibody; PTPBR7 antibody; PTPRQ antibody; PTPRR antibody; R PTP R antibody

Rabbit IgG

This antibody was obtained by immunization of PTPRR recombinant protein (Accession Number: NM_130846). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

PTPRR(protein tyrosine phosphatase, receptor type, R) is also named as PCPTP1, PTP-SL, PTPBR7 and belongs to the protein-tyrosine phosphatase family. It sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. It has four isoforms that they have molecular weights of 72, 60, 42 and 37 kDa, respectively, and differ in the length of their N-terminal part which result in distinct subcellular localizations. All PTPRR isoforms are found to be short-lived proteins, with half-lives of around 3-5 hours, and are constitutively phosphorylated on one or two of the previously identified protein kinase A and MAP kinase target sites.

• Munkley J, Lafferty NP, Kalna G. Androgen-regulation of the protein tyrosine phosphatase PTPRR activates ERK1/2 signalling in prostate cancer cells. BMC cancer. 15:9. 2015.