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Product Name
PTPN18 antibody
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Description
PTPN18 Rabbit Polyclonal antibody. Positive IHC detected in human brain tissue. Positive WB detected in Jurkat cells, human brain tissue. Observed molecular weight by Western-blot: 50kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
BDP1 antibody; Brain derived phosphatase antibody; PTP HSCF antibody; PTPN18 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PTPN18 recombinant protein (Accession Number: NM_001142370). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:114317(PTPN18 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human brain using Catalog No:114317(PTPN18 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human brain using Catalog No:114317(PTPN18 antibody) at dilution of 1:100 (under 40x lens)
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Background
PTPN18(Tyrosine-protein phosphatase non-receptor type 18) is also named as BDP1 and belongs to the protein-tyrosine phosphatase family. The PTPN18 cDNA encodes a deduced 459-amino acid protein with no transmembrane domain and a calculated molecular weight of 50 kD. PTPN18 has a PEST motif and shares the greatest homology with members of the PTP-PEST gene family. Northern blot analysis indicated that PTPN18 is expressed not only in brain, but also in colon and several different tumor-derived cell lines.(PMID:8950995). It has 2 isoforms produced by alternative splicing.
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