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Product Name
PTPN14 antibody
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Description
PTPN14 Rabbit Polyclonal antibody. Positive WB detected in K-562 cells, HeLa cells. Positive IHC detected in human placenta tissue, human brain tissue, human kidney tissue, human lung tissue, human ovary tissue, human skin tissue, human spleen tissue. Observed molecular weight by Western-blot: 150 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
PEZ antibody; PTP36 antibody; PTPN14 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PTPN14 recombinant protein (Accession Number: XM_047426370). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:114316(PTPN14 antibody) at dilution of 1:400
Immunohistochemical of paraffin-embedded human placenta using Catalog No:114316(PTPN14 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human placenta using Catalog No:114316(PTPN14 antibody) at dilution of 1:50 (under 40x lens)
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Background
PTPN14 (tyrosine-protein phosphatase non-receptor type 14) is also named as PEZ and belongs to the protein-tyrosine phosphatase family and non-receptor class subfamily. It is a multi-domain protein expressed in breast, kidney, skeletal muscle, lung, placenta, and characterized by an N-terminal FERM domain and a C-terminal PTP domain with an intervening sequence containing an acidic region and a putative SH3 domain-binding sequence (PMID: 21701840). Defects in PTPN14 are a cause of choanal atresia and lymphedema (CHATLY).
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