PSMB4 antibody

PSMB4 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PSMB4 Rabbit Polyclonal antibody. Positive IF detected in MCF-7 cells, HepG2 cells. Positive IHC detected in human breast cancer tissue. Positive WB detected in HEK-293 cells, HeLa cells, human placenta tissue, human skeletal muscle tissue, MCF-7 cells, mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 25 kDa

ELISA, IHC, IF, WB

Human; other species not tested.

20S proteasome antibody; 26 kDa prosomal protein antibody; HN3 antibody; HsBPROS26 antibody; HsN3 antibody; Macropain beta chain antibody; PROS 26 antibody; PROS26 antibody; Proteasome beta chain antibody; Proteasome chain 3 antibody; Proteasome subunit beta type 4 antibody; PSMB4 antibody

Rabbit IgG

This antibody was obtained by immunization of PSMB4 recombinant protein (Accession Number: BC010088). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

PSMB4(Proteasome subunit beta type-4) is also named as PROS26 and belongs to the peptidase T1B family. The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The human protein PSMB4 is known mainly as an interaction partner for several proteins, suggesting an important function of binding not only to the lid, but also to the 20 S core of the proteasome. PSMB4 might be a major site for proteasome regulation, where signals from the outside might be transduced to the protease activities inside(PMID:15660529 ). The full length 30 kDa protein has a propeptide of 45 amino acid.

• Lee GY, Haverty PM, Li L. Comparative oncogenomics identifies PSMB4 and SHMT2 as potential cancer driver genes. Cancer research. 74(11):3114-26. 2014.