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Product Name
PSMA3 antibody
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Description
PSMA3 Rabbit Polyclonal antibody. Positive IHC detected in human lymphoma tissue. Positive WB detected in human lung tissue, HeLa cells, NIH/3T3 cells. Observed molecular weight by Western-blot: 28kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
20S proteasome antibody; HC8 antibody; Macropain subunit C8 antibody; Proteasome component C8 antibody; PSC3 antibody; PSC8 antibody; PSMA3 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PSMA3 recombinant protein (Accession Number: NM_002788). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human lung tissue were subjected to SDS PAGE followed by western blot with Catalog No:114374(PSMA3 antibody) at dilution of 1:400
Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:114374(PSMA3 antibody) at dilution of 1:50 (under 10x lens)
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Background
PSMA3(Proteasome subunit alpha type-3) is also named as HC8, PSC8 and belongs to the peptidase T1A family. The proteasome is a multicatalytic protease complex that catalyzes an energy-dependent, extralysosomal proteolytic pathway responsible for selective elimination of proteins with aberrant structures and naturally occurring short-lived proteins related to metabolic regulation and cell cycle progression. It has 2 isoforms produced by alternative splicing.
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References
- Just J, Jung T, Friis NA. Identification of an unstable 4-hydroxynoneal modification on the 20S proteasome subunit α7 by recombinant antibody technology. Free radical biology & medicine. 89:786-92. 2015.
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