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Product Name
Mouse Coagulation Factor II/F2 (His Tag) recombinant protein
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Description
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).
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Protein name
Prothrombin
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Protein short names
PT; THROMBIN; THPH1; COAGULATION FACTOR II; FII; CF-2; PROTHROMBIN; F2; RPRGL2; RP23-176N9.4; CF2
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Uniprot ID
Q3TJ94
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Gene Name
F2; Cf2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the full length of mouse F2 (NP_034298.1) (Met 1-Gly 618) was expressed, with a C-terminal polyhistidine tag.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse F2 consists of 605 amino acids (pro form) and has a calculated molecular mass of 69.3 kDa. The apparent molecular mass of the recombinant mouse F2 is approximately 85 kDa in SDS-PAGE under reducing conditions.
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Purity
> 96 % as determined by SDS-PAGE
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Activity
Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC R&D Systems, Catalog # ES011.
The specific activity is > 2000 pmoles/min/μg. -
Validations
Mouse Coagulation Factor II / FII / F2 Protein (His Tag) SDS-PAGE
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