PRDM10 antibody

Cat.#: 114172

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Product Information

  • Product Name
    PRDM10 antibody
  • Documents
  • Description
    PRDM10 Rabbit Polyclonal antibody. Positive IP detected in mouse testis tissue. Positive WB detected in HEK-293 cells, mouse testis tissue, NIH/3T3 cells. Observed molecular weight by Western-blot: 120-150 kDa
  • Tested applications
    ELISA, IP, WB
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    KIAA1231 antibody; PFM7 antibody; PR domain containing 10 antibody; PRDM10 antibody; TRIS antibody; Tristanin antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of PRDM10 recombinant protein (Accession Number: NM_199437). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:2000

  • Validations

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:114172(PRDM10 antibody) at dilution of 1:1000

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:114172(PRDM10 antibody) at dilution of 1:1000

    IP Result of anti-PRDM10 (IP:Catalog No:114172, 5ug; Detection:Catalog No:114172 1:500) with mouse testis tissue lysate 8000ug.

    IP Result of anti-PRDM10 (IP:Catalog No:114172, 5ug; Detection:Catalog No:114172 1:500) with mouse testis tissue lysate 8000ug.

  • Background
    PRDM10 is a member of PRDM family, which contains a PR(PRDI-BF1 and RIZ homology) domain, and PRDM is also a subgroup of PR/SET transcription factor family for its PR domain is similar to the catalytic motif of the SET domain of histone methyltransferase(HMTase). Thus PRDM is suggested involve in the regulation of genome expression and chromatin remodeling. PRDM10 shares characteristics with the PR/SET faimly and clusters of zinc fingers DNA binding motifs. It's postualated PRDM10 has an essential role in regulating gene expression and tissue differentiation and a gene repressor. It may play a role in the pathogenesis of gangliosidosis.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"