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Product Name
PLSCR4 antibody
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Description
PLSCR4 Rabbit Polyclonal antibody. Positive WB detected in human heart tissue, human brain tissue, human liver tissue, human placenta tissue. Observed molecular weight by Western-blot: 37kd
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Tested applications
ELISA, WB
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
PLSCR4 antibody; phospholipid scramblase 4 antibody; PL scramblase 4 antibody; TRA1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PLSCR4 recombinant protein (Accession Number: XM_011513031). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:114014(PLSCR4 antibody) at dilution of 1:400
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Background
PLSCR4 (Phospholipid scramblase 4) belongs to the phospholipid scramblase family which is thought to mediate the loss of lipid asymmetry. Elimination of this lipid bilayer asymmetry is an important physiological process and appears to occur as a result of elevated intracellular calcium concentration, or occur with cell activation, injury, and apoptosis.PLSCR4 also plays a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
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References
- McLean KC, Oppenheimer KH, Sweet LM, Phillippe M. Phospholipid scramblase expression in the pregnant mouse uterus in LPS-induced preterm delivery. Reproductive sciences (Thousand Oaks, Calif.). 19(11):1211-8. 2012.
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