PHAX antibody

PHAX antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PHAX Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, HepG2 cells. Observed molecular weight by Western-blot: 55 kDa

ELISA, WB

Human,Mouse,Rat; other species not tested.

FLJ13193 antibody; PHAX antibody; RNUXA antibody

Rabbit IgG

This antibody was obtained by immunization of PHAX recombinant protein (Accession Number: NM_032177). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Small nuclear and small nucleolar RNAs (snRNAs and snoRNAs) are essential components of snRNPs and snoRNPs, and have a critical role in the maturation of, respectively, mRNAs and rRNAs within the nucleus of eukaryotic cells. Complex and specific pathways exist for the assembly of snRNPs and snoRNPs, involving, nucleocytoplasmic transport of snRNAs and intranuclear transport between compartments of snoRNAs. In metazoa, a subset of spliceosomal snRNAs are exported from the nucleus after transcription. This export occurs in a large complex containing a snRNA, the nuclear cap binding complex (CBC), RanGTP, the leucine-rich nuclear export signal receptor CRM1/Xpo1, and the recently identified phosphoprotein PHAX (phosphorylated adaptor for RNA export). PHAX contains a conserved single-stranded nucleic acid binding domain (RNA_GG_bind domain) with no sequence homology with any other known RNA-binding module [PMID:15574332,11333016, 15574332]