PGCP antibody

PGCP antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PGCP Rabbit Polyclonal antibody. Positive IF detected in L02 cells. Positive WB detected in L02 cells, human placenta tissue, human serum tissue, mouse kidney tissue. Positive IP detected in mouse kidney tissue. Observed molecular weight by Western-blot: 65-70 kDa

ELISA, WB, IF, IP

Human, Mouse; other species not tested.

CPQ antibody; LCH1 antibody; Lysosomal dipeptidase antibody; PGCP antibody; plasma glutamate carboxypeptidase antibody

Rabbit IgG

This antibody was obtained by immunization of PGCP recombinant protein (Accession Number: NM_016134). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

PGCP(plasma glutamate carboxypeptidase) is also named as LCH1,CPQ and belongs to the peptidase M28 family. It may play an important role in the hydrolysis of circulating peptides. It catalyzes more efficiently the hydrolysis of dipeptides with unsubstituted terminals into amino acids. It is a proteinase that acts on the unsubstituted N- and C-termini of dipeptides. It has been suggested that this PGCP is involved in the release of thyroxine(PMID:20951214). Human PGCP is a metallopeptidase with five potential glycosylation sites, whose activity depends on dimerizationand it can be detected a band of 65-72kd in FRTL-5 cells which is pro-PGCP(PMID:22127294). It can be N-glycosylated(PMID:10206990). It has the pro-form of 60-65 kDa and mature form of 55 kDa(PMID:20951214).