PGAM2 antibody

Cat.#: 113776

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Product Information

  • Product Name
    PGAM2 antibody
  • Documents
  • Description
    PGAM2 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue. Observed molecular weight by Western-blot: 29 kDa
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    BPG dependent PGAM 2 antibody; PGAM M antibody; PGAM2 antibody; PGAMM antibody; Phosphoglycerate mutase 2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_000290). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:113776(PGAM2 Antibody) at dilution of 1:600

    mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:113776(PGAM2 Antibody) at dilution of 1:600

  • Background
    Phosphoglycerate mutase (PGAM), an important enzyme in the glycolytic pathway, catalyzes the transfer of a phosphate group between the 2 and the 3 positions of glyceric acid. The muscle-specific isoform (type M, PGAM2) of phosphoglycerate mutase (PGAM) is a housekeeping enzyme and it catalyzes the conversion of 3-phosphoglycerate into 2-phosphoglycerate in the glycolysis process to release energy. It is encoded by the Pgam2 gene. In addition, it is demonstrated that PGAM2 locates both in cytoplasm and nuclei, and takes part in the glycometabolism process of cytoplasm and nuclei(PMID: 18499067). Defects in PGAM2 are the cause of glycogen storage disease type 10 (GSD10).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"