PCDHA2 antibody

Cat.#: 113693

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Product Information

  • Product Name
    PCDHA2 antibody
  • Documents
  • Description
    PCDHA2 Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, HeLa cells, human heart tissue, Raji cells. Positive IP detected in HeLa cells. Observed molecular weight by Western-blot: 80 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    PCDH alpha 2 antibody; PCDH ALPHA2 antibody; PCDHA2 antibody; protOCadherin alpha 2 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of PCDHA2 recombinant protein (Accession Number: NM_031496). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:200-1:1000

  • Validations

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:113693(PCDHA2 antibody) at dilution of 1:800

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:113693(PCDHA2 antibody) at dilution of 1:800

    IP Result of anti-PCDHA2 (IP:Catalog No:113693, 3ug; Detection:Catalog No:113693 1:300) with HeLa cells lysate 4650ug.

    IP Result of anti-PCDHA2 (IP:Catalog No:113693, 3ug; Detection:Catalog No:113693 1:300) with HeLa cells lysate 4650ug.

  • Background
    Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). PCDHA2 (protocadherin alpha 2) is a single-pass type I membrane protein containing 6 cadherin domains. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"