PAPD5 antibody

PAPD5 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PAPD5 Rabbit Polyclonal antibody. Positive IP detected in Jurkat cells. Observed molecular weight by Western-blot: 63-80 kDa

ELISA, IP

Human; other species not tested.

FLJ40270 antibody; PAPD5 antibody; Terminal uridylyltransferase 3 antibody; TRF4 2 antibody; TUTase 3 antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_001040285). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

PAPD5, also named as Non-canonical poly(A) RNA polymerase PAPD5, is a 572 amino acid protein, which contains 1 PAP-associated domain and belongs to the DNA polymerase type-B-like family. PAPD5 is predominantly expressed in the cytoplasm. PAPD5 as catalytic subunit of a TRAMP-like complex that has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. PAPD5 plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. PAPD5 also may play a role in sister chromatid cohesion. The calculated molecular weight of PAPD5 is a 63 kDa, but the post-modified protein is about 80 kDa.