-
Product Name
PAI-1 antibody
- Documents
-
Description
PAI-1 Mouse Monoclonal antibody. Positive WB detected in SH-SY5Y cells, human plasma tissue, pig liver tissue. Positive IF detected in HepG2 cells. Observed molecular weight by Western-blot: 45-50 kDa
-
Tested applications
ELISA, IF, WB
-
Species reactivity
Human, Pig; other species not tested.
-
Alternative names
PAI antibody; PAI 1 antibody; PAI1 antibody; PLANH1 antibody; Serpin E1 antibody; SERPINE1 antibody
-
Isotype
Mouse IgG1
-
Preparation
This antibody was obtained by immunization of PAI-1 recombinant protein (Accession Number: NM_000602). Purification method: Protein G purified.
-
Clonality
Monoclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:1000-1:10000
IF: 1:20-1:200
-
Validations
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:107449(SERPINE1 Antibody) at dilution of 1:2000
Immunofluorescent analysis of (-20oc Ethanol) fixed HepG2 cells using Catalog No:107449(SERPINE1 Antibody) at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L)
-
Background
SERPINE1, also named as Plasminogen activator inhibitor type 1 (PAI-1), is a member of the serine protease inhibitor (SERPIN) superfamily. PAI-1 is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"