-
Product Name
p57Kip2 antibody
- Documents
-
Description
p57Kip2 Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells. Positive IHC detected in human placenta tissue. Observed molecular weight by Western-blot: 57 kDa
-
Tested applications
ELISA, IHC, WB
-
Species reactivity
Human; other species not tested.
-
Alternative names
BWCR antibody; BWS antibody; CDKN1C antibody; KIP2 antibody; p57 antibody; p57Kip2 antibody; WBS antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of p57Kip2 recombinant protein (Accession Number: XM_017017088). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
-
Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:113554(CDKN1C Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human placenta tissue slide using Catalog No:113554(CDKN1C Antibody) at dilution of 1:200 (under 10x lens)
Immunohistochemistry of paraffin-embedded human placenta tissue slide using Catalog No:113554(CDKN1C Antibody) at dilution of 1:200 (under 40x lens)
-
Background
CDKN1C, also named as p57KIP2 and KIP2, belongs to the CDI family. CDKN1C is a potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. It is a negative regulator of cell proliferation. CDKN1C may play a role in maintenance of the non-proliferative state throughout life.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"