-
Product Name
P-selectin antibody
- Documents
-
Description
P-selectin Mouse Monoclonal antibody. Positive IHC detected in human spleen tissue. Positive IP detected in K-562 cells. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 105-110 kDa
-
Tested applications
ELISA, IHC, WB, IP
-
Species reactivity
Human; other species not tested.
-
Alternative names
CD62 antibody; CD62P antibody; FLJ45155 antibody; GMP 140 antibody; GMP140 antibody; GMRP antibody; Granule membrane protein 140 antibody; GRMP antibody; LECAM3 antibody; P selectin antibody; PADGEM antibody; PSEL antibody; P-selectin antibody; SELP antibody
-
Isotype
Mouse IgG2b
-
Preparation
This antibody was obtained by immunization of P-selectin recombinant protein (Accession Number: XM_005245438). Purification method: Protein A purified.
-
Clonality
Monoclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
IHC: 1:20-1:200
-
Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:107488(SELP Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human spleen tissue slide using Catalog No:107488(SELP Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human spleen tissue slide using Catalog No:107488(SELP Antibody) at dilution of 1:50 (under 40x lens)
IP Result of anti-SELP (IP:Catalog No:107488, 5ug; Detection:Catalog No:107488 1:600) with K-562 cells lysate 1760ug.
-
Background
P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"