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Product Name
ONECUT2 antibody
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Description
ONECUT2 Rabbit Polyclonal antibody. Positive WB detected in mouse skin tissue, A549 cells, HEK-293 cells, HeLa cells, HepG2 cells, Jurkat cells. Positive IP detected in HEK-293 cells. Observed molecular weight by Western-blot: 55-60 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
HNF 6 beta antibody; HNF6B antibody; OC 2 antibody; OC2 antibody; One cut domain family member 2 antibody; one cut homeobox 2 antibody; ONECUT2 antibody; Transcription factor ONECUT 2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ONECUT2 recombinant protein (Accession Number: BC108925). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
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Validations
mouse skin tissue were subjected to SDS PAGE followed by western blot with Catalog No:113350(ONECUT2 Antibody) at dilution of 1:600
IP Result of anti-ONECUT2 (IP:Catalog No:113350, 4ug; Detection:Catalog No:113350 1:300) with HEK-293 cells lysate 3200ug.
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Background
ONECUT2, also named as One cut domain family member 2 or Hepatocyte nuclear factor 6-beta, is a 504 amino acid protein, which contains one CUT DNA-binding domain and one homeobox DNA-binding domain. ONECUT2 belongs to the CUT homeobox family and activates the transcription of a number of liver genes such as HNF3B. ONECUT2 is required for liver differnetiation and metabolism. ONECUT2 and ONECUT3 play redundant roles with ONECUT1 in pancreas development.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"