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OCT2-Specific antibody

Cat.#: 106993

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Product Information

  • Product Name
    OCT2-Specific antibody
  • Documents
  • Description
    OCT2-Specific Rabbit Polyclonal antibody. Positive WB detected in mouse thymus tissue, human brain tissue, human spleen tissue, mouse kidney tissue, Raji cells. Positive IHC detected in human spleen tissue. Observed molecular weight by Western-blot: 55 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    OCT2 antibody; OCtamer binding protein 2 antibody; OTF 2 antibody; OTF2 antibody; POU class 2 homeobox 2 antibody; POU2F2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_002698). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    mouse thymus tissue were subjected to SDS PAGE followed by western blot with Catalog No:113471(POU2F2-Specific antibody) at dilution of 1:300

    mouse thymus tissue were subjected to SDS PAGE followed by western blot with Catalog No:113471(POU2F2-Specific antibody) at dilution of 1:300

    Immunohistochemical of paraffin-embedded human spleen using Catalog No:113471(POU2F2-Specific antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human spleen using Catalog No:113471(POU2F2-Specific antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human spleen using Catalog No:113471(POU2F2-Specific antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human spleen using Catalog No:113471(POU2F2-Specific antibody) at dilution of 1:100 (under 40x lens)

  • Background
    ocT2, also named as POU2F2 and OTF2, belongs to the POU transcription factor family and Class-2 subfamily. ocT2 is a transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). ocT2 regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. It modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. The antibody is specific to ocT2.
  • References
    • Wen J, Zeng M, Shu Y. Aging increases the susceptibility of cisplatin-induced nephrotoxicity. Age (Dordrecht, Netherlands). 37(6):112. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"