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Product Name
NXF2 antibody
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Description
NXF2 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue. Positive IP detected in mouse testis tissue. Positive IHC detected in human lymphoma tissue. Observed molecular weight by Western-blot: 72 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Cancer/testis antigen 39 antibody; CT39 antibody; FLJ20416 antibody; nuclear RNA export factor 2 antibody; NXF2 antibody; NXF2B antibody; TAP like protein 2 antibody; TAPL 2 antibody; TAPL2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of NXF2 recombinant protein (Accession Number: NM_022053). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:1000
IHC: 1:20-1:200
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Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:113452(NXF2 antibody) at dilution of 1:400
Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:113452(NXF2 antibody) at dilution of 1:50 (under 10x lens)
IP Result of anti-NXF2 (IP:Catalog No:113452, 4ug; Detection:Catalog No:113452 1:400) with mouse testis tissue lysate 4000ug.
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Background
NXF2, also named as Nuclear RNA export factor 2 or TAPL2, is a 626 amino acid protein, which contains one TAP-C domain, one RRM domain, one NTF2 domain, and four LRR repeats. NXF2 belongs to the NXF family and is expressed almost exclusively in testis.NXF2 localizes in the nucleus and is involved in the export of mRNA from the nucleus to the cytoplasm.
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References
- Yin Y, Wang G, Liang N. Nuclear export factor 3 is involved in regulating the expression of TGF-β3 in an mRNA export activity-independent manner in mouse Sertoli cells. The Biochemical journal. 452(1):67-78. 2013.
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