NR2F6 antibody

NR2F6 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

NR2F6 Mouse Monoclonal antibody. Positive WB detected in HEK-293 cells, HeLa cells. Positive IHC detected in human kidney tissue. Observed molecular weight by Western-blot: 43 kDa

ELISA, IHC, WB

Human, Mouse; other species not tested.

EAR 2 antibody; EAR2 antibody; ERBAL2 antibody; NR2F6 antibody; V erbA related protein 2 antibody

Mouse IgG1

This antibody was obtained by immunization of NR2F6 recombinant protein (Accession Number: NM_005234). Purification method: Antigen affinity purified.

Monoclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

NR2F6 belongs to NR2F subfamily members, which have their roles in the regulation of neurogenesis, organogenesis, and cellular differentiation during embryonic development [PMID:15875024]. NR2F6 acts as transcription factor by binding to a TGACCT direct-repeat motif and has been established in controlling facets of central nervous system (CNS) [12690040]. It is a nuclear attenuator that directly interferes with DNA binding of NF-AT and, subsequently, transcriptional activity of the NF-AT-dependent IL-17 expression. Otherwise, NR2F6 negatively interfered with transcriptional cytokine responses and acted as a barrier against autoimmunity [PMID:18701084].