nNOS antibody

Cat.#: 113259

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Product Information

  • Product Name
    nNOS antibody
  • Documents
  • Description
    nNOS Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue.
  • Tested applications
    ELISA, IHC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    bNOS antibody; Constitutive NOS antibody; IHPS1 antibody; N NOS antibody; NC NOS antibody; Neuronal NOS antibody; Nitric oxide synthase antibody; brain antibody; nNOS antibody; NOS antibody; NOS type I antibody; NOS1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_000620). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    IHC: 1:20-1:200

  • Validations

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:113259(nNOS antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:113259(nNOS antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:113259(nNOS antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:113259(nNOS antibody) at dilution of 1:100 (under 40x lens)

  • Background
    nNOS belongs to the NOS family. NOS1 produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. NO is synthesized from L-arginine by nitric oxide synthases. NOS1 is a nitric oxide synthase which is highly expressed in skeletal muscle. Genetic variations in NOS1 gene are associated with susceptibility to infantile hypertrophic pyloric stenosis type 1 (IHPS1).The antibody can recognize isoform 1,2,4 of NOS1.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"