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Product Name
NME5 antibody
- Documents
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Description
NME5 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue, human brain tissue, human kidney tissue. Positive IHC detected in human prostate tissue. Observed molecular weight by Western-blot: 24kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
IPIA beta antibody; NDK H 5 antibody; NDP kinase homolog 5 antibody; NME5 antibody; Testis specific nm23 homolog antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of NME5 recombinant protein (Accession Number: NM_003551). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:113249(NME5 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human prostate using Catalog No:113249(NME5 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human prostate using Catalog No:113249(NME5 antibody) at dilution of 1:100 (under 40x lens)
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Background
NME5(Nucleoside diphosphate kinase homolog 5) belongs to the NDK family. Its expression plays a critical role in spermiogenesis by increasing the cellular levels of GPX5 to eliminate reactive oxygen species. NME5 may have specific functions in the phosphotransfer network involved in spermiogenesis and flagellar movement.
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References
- Parris TZ, Kovács A, Aziz L. Additive effect of the AZGP1, PIP, S100A8 and UBE2C molecular biomarkers improves outcome prediction in breast carcinoma. International journal of cancer. 134(7):1617-29. 2014.
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