NKX3-1 antibody

NKX3-1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

NKX3-1 Rabbit Polyclonal antibody. Positive WB detected in human testis tissue. Observed molecular weight by Western-blot: 36kd

ELISA, WB

human, mouse, rat; other species not tested.

NKX3 antibody; NKX3 1 antibody; NKX3.1 antibody; NKX3A antibody; NK3 homeobox 1 antibody

Rabbit IgG

This antibody was obtained by immunization of NKX3-1 recombinant protein (Accession Number: NM_006167). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

NKX3-1, also named as NKX3.1 and NKX3A, belongs to the NK-3 homeobox family. It is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. NKX3-1 plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. It act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells(PMID:19462257).