NINJ2 antibody

Cat.#: 107333

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Product Information

  • Product Name
    NINJ2 antibody
  • Documents
  • Description
    NINJ2 Mouse Monoclonal antibody. Positive IHC detected in human tonsillitis tissue. Positive WB detected in Transfected HEK-293 cells.
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    FLJ56349 antibody; Nerve injury induced protein 2 antibody; NINJ2 antibody; ninjurin 2 antibody
  • Isotype
    Mouse IgG2b
  • Preparation
    This antibody was obtained by immunization of NINJ2 recombinant protein (Accession Number: BC057766). Purification method: Protein A purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    Untransfected and NINJ2 transfected HEK-293 cells were subjected to SDS-PAGE followed by western blot with Catalog No:107333 (mouse anti-NINJ2 monoclonal antibody,1:1000) and mouse anti-6*His tag respectively.

    Untransfected and NINJ2 transfected HEK-293 cells were subjected to SDS-PAGE followed by western blot with Catalog No:107333 (mouse anti-NINJ2 monoclonal antibody,1:1000) and mouse anti-6*His tag respectively.

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:107333(NINJ2 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:107333(NINJ2 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:107333(NINJ2 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:107333(NINJ2 Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    NINJ2 (Ninjurin2) is a member of the ninjurin family of adhesion molecules which mediate cell-to-cell and cell-to-extracellular matrix interactions during development, differentiation, and regeneration of the peripheral nervous system. The gene encodes NINJ2 is located on chromosome 12p13. NINJ2 mRNA is widely expressed in adult human tissues, with highest level in bone marrow, followed by peripheral leukocytes, lung, and lymph nodes. In the peripheral nervous system, NINJ2 is expressed constitutively in mature sensory and enteric neurons. The expression of NINJ2 is upregulated after nerve injury in Schwann cells, suggesting that it may promote nerve regeneration. It may also play an important role in the pathogenesis of inflammatory disorder. (PMID: 10627596)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"