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Product Name
NFYC antibody
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Description
NFYC Rabbit Polyclonal antibody. Positive WB detected in K-562 cells. Observed molecular weight by Western-blot: 48 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CBF C antibody; CBFC antibody; DKFZp667G242 antibody; FLJ45775 antibody; H1TF2A antibody; HAP5 antibody; HSM antibody; NF YC antibody; NFYC antibody; Transactivator HSM 1/2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of NFYC recombinant protein (Accession Number: XM_017001368). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:113168(NFYC antibody) at dilution of 1:1000
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Background
NFYC, also named as Nuclear transcription factor Y subunit gamma or Transactivator HSM-1/2, is a 458 amino acid protein, which belongs to the NFYC/HAP5 subunit family. NFYC localizes in the nucleus and stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes. SP1, NFYC and FOXO3, FOXO4 transcription factors are involved in the regulation of STK11 transcription.
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References
- Tong Z, Fan Y, Zhang W. Pancreas-specific Pten deficiency causes partial resistance to diabetes and elevated hepatic AKT signaling. Cell research. 19(6):710-9. 2009.
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